If you’ve been researching weight loss medications, you’ve likely come across two names: Ozempic and Wegovy. Both are weekly injections containing semaglutide, a GLP-1 receptor agonist that works by mimicking a natural hormone in the body that helps regulate blood sugar and appetite.

But despite sharing the same active ingredient, Ozempic and Wegovy are not the same medication—especially here in the UK. At Pharmaesthetics, we’re often asked what the difference is, and more importantly, which one is appropriate for weight loss treatment.

In this blog, we’ll break down the key differences between Ozempic and Wegovy, how they’re licensed in the UK, and why Wegovy is the approved option for medical weight loss at our clinic.

What Is Ozempic?

Ozempic was originally developed and licensed for managing type 2 diabetes. It helps improve blood sugar control by:

• –> Stimulating insulin production

• –> Reducing glucagon secretion

• –> Slowing down gastric emptying (which helps you feel full longer)

Although many people taking Ozempic for diabetes experienced significant weight loss, it was not specifically approved as a weight management drug in the UK. For a time, some clinicians prescribed it “off-label” to help with weight loss in patients without diabetes, especially when Wegovy wasn’t yet available.

However, due to supply issues and increasing demand, Ozempic UK guidelines now prioritise its use strictly for diabetes management. Prescribing it off-label for weight loss is no longer recommended.

What Is Wegovy?

Wegovy is the official weight loss version of semaglutide, manufactured by the same company that makes Ozempic. It’s specifically formulated and licensed for adults with:

• –> A BMI of 30 or above, or

• –> A BMI of 27 or above with a weight-related condition (e.g. high blood pressure, sleep apnoea, prediabetes)

Wegovy is part of a medically supervised weight loss programme, and it’s designed to be used alongside lifestyle changes such as improved diet, increased physical activity, and behavioural support.

The dosage of semaglutide in Wegovy also increases more gradually than in Ozempic, and ultimately reaches a higher weekly dose (2.4 mg vs 1.0 mg). This higher dose has been shown in clinical trials to produce greater weight loss results than the lower doses used for diabetes.

Key Differences Between Ozempic and Wegovy in the UK

Why We Provide Wegovy, Not Ozempic

At Pharmaesthetics, we are committed to offering safe, regulated, and evidence-based weight loss support. That’s why we provide Wegovy—not Ozempic—for our clients seeking weight management treatment.

Wegovy is licensed for weight loss in the UK, meaning it has undergone rigorous clinical trials and regulatory review specifically for that purpose. By contrast, using Ozempic for weight loss—while once common—is no longer considered best practice, especially in light of ongoing medication shortages affecting people with diabetes.

How Wegovy Works for Weight Loss

Wegovy helps with weight loss in several key ways:

• –> It reduces appetite and cravings

• –> It slows down digestion, helping you feel full for longer

• –> It helps lower caloric intake naturally, without the feeling of restriction

When used alongside a healthy eating plan, increased physical activity, and the support of a medical team, Wegovy has been shown to help people lose 10–15% of their body weight on average.

At Pharmaesthetics, our weight loss programmes include:

• –> A full medical consultation to assess suitability

• –> Prescription of Wegovy where appropriate

• –> Ongoing support, monitoring, and check-ins to track your progress

• –> Lifestyle and nutrition guidance to maximise results

Ready to Start Your Weight Loss Journey?

If you’ve been searching for Ozempic UK information to help you lose weight, it’s important to understand the shift in current medical guidance. While Ozempic is an excellent treatment for diabetes, Wegovy is the right and approved choice for weight loss in the UK.

At Pharmaesthetics, we offer a private, clinician-led weight loss service using Wegovy safely and effectively to help you achieve your goals.

Book a comprehensive weight loss appointment today and take the first step towards a healthier, more confident you—with expert support every step of the way.

This blog was written on behalf of Pharmaesthetics Central by Pharmacy Mentor.